List of adverse effects of chlorpromazine

Chlorpromazine includes the following list of adverse effects (serious adverse effects appear in bold):

Very common

 * Sedation (cf. "Thorazine shuffle" – a shuffling gait due to sedation)
 * Somnolence
 * Extrapyramidal symptoms
 * Weight gain
 * Orthostatic hypotension
 * Dry mouth
 * Constipation

Common

 * ECG changes
 * Contact dermatitis
 * Sensitivity to light
 * Urticaria (hives)
 * Maculopapular rash
 * Petechia or edema
 * Hyperprolactinaemia
 * Impaired thermoregulation
 * Hyperglycaemia
 * Other hypothalamic abnormalities
 * Blurred vision
 * Confusion
 * Raised ANA titre
 * Positive SLE cells
 * Mydriasis
 * Atonic colon
 * Seizure
 * Psychomotor agitation|Agitation (restlessness)
 * Pain at the injection site
 * Injection site abscess

Uncommon

 * Miosis
 * Urinary retention
 * Nasal congestion
 * Nausea
 * Obstipation
 * Arrhythmias
 * Skin pigmentation
 * Glycosuria
 * Hypoglycaemia
 * Paralytic ileus

Rare

 * Agranulocytosis
 * Haemolytic anaemia
 * Aplastic anaemia
 * A-V block
 * Hypertensive crises
 * Thrombocytopenic purpura
 * Exfoliative dermatitis
 * Toxic epidermal necrolysis
 * Systemic lupus erythematosus
 * Syndrome of inappropriate secretion of antidiuretic hormone (SIADH)
 * Water retention
 * Cholestatic jaundice
 * Liver injury
 * Neuroleptic malignant syndrome
 * Myasthenia gravis

Unknown frequency

 * Leucopaenia
 * Eosinophilia
 * Pancytopaenia
 * Priapism
 * Photophobia
 * Corneal deposits
 * Respiratory depression
 * Ventricular tachycardia
 * QT interval prolongation
 * Atrial fibrilation
 * Hyperthermia
 * Hypothermia
 * Galactorrhoea
 * Breast enlargement in either sex
 * False-positive pregnancy tests
 * Allergic reaction
 * Fits
 * Cerebral oedema
 * Urinary incontinence
 * Coagulation defects
 * Nightmares
 * Abnormality of cerebrospinal fluid proteins
 * Dysphoria
 * Catatonic excitement
 * Narrow angle glaucoma
 * Optic atrophy
 * Pigmentary retinopathy
 * Amenorrhoea
 * Infertility
 * Tardive dyskinesia