List of adverse effects of venlafaxine

The following list shows the rates of adverse symptoms seen in people taking venlafaxine.

Very common (>10% incidence)

 * Headache — an often transient side effect that is common to most serotonin reuptake inhibitors and that most often occurs at the beginning of therapy or after a dose escalation.
 * Nausea — an adverse effect that is more common with venlafaxine than with the SSRIs. Usually transient and less severe in those receiving the extended release formulations.
 * Insomnia
 * Asthenia (weakness)
 * Dizziness
 * Ejaculation disorder — sexual side effects can be seen with virtually any antidepressant, especially those that inhibit the reuptake of serotonin (including venlafaxine).
 * Somnolence
 * Dry mouth
 * Sweating
 * Withdrawal

Common (1–10% incidence)

 * Constipation
 * Nervousness
 * Abnormal vision
 * Anorgasmia
 * Hypertension
 * Impotence
 * Paresthesia
 * Tremor
 * Vasodilation
 * Vomiting
 * Weight loss
 * Chills
 * Palpitations
 * Confusion
 * Depersonalization
 * Night sweats
 * Menstrual disorders associated with increased bleeding or increased irregular bleeding (e.g. menorrhagia, metrorrhagia)
 * Urinary frequency increased
 * Abnormal dreams
 * Decreased libido
 * Increased muscle tonus
 * Yawning
 * Abnormality of accommodation
 * Abnormal ejaculation/orgasm (males)
 * Urinary hesitancy
 * Serum cholesterol increased (especially when treatment is prolonged and it may be dose-dependent)

Uncommon (0.1-1% incidence)

 * Face edema (Swelling)
 * Intentional injury (Self-injury)
 * Malaise
 * Moniliasis (Candidiasis/Thrush)
 * Neck stiffness
 * Pelvic pain
 * Photosensitivity reaction
 * Suicide attempt
 * Withdrawal syndrome
 * Hypotension (Low blood pressure)
 * Postural hypotension
 * Syncope (Fainting)
 * Tachycardia (High heart rate)
 * Bruxism (Teeth grinding)
 * Ecchymosis (Bruising)
 * Mucous membrane bleeding
 * Gastrointestinal bleeding
 * Abnormal liver function tests
 * Hyponatraemia (Low blood sodium)
 * Weight gain
 * Apathy
 * Hallucinations
 * Myoclonus (Twitching or Muscle spasm)
 * Rash
 * Abnormal orgasm (females)
 * Urinary retention (Inability to pass urine)
 * Angioedema (Swelling of skin or mucus membranes)
 * Agitation
 * Impaired coordination & balance
 * Alopecia (Hair loss)
 * Tinnitus (Ringing in the ears, Hearing sounds)
 * Proteinuria (Protein in urine)

Rare (0.01–0.1% incidence)

 * Syndrome of inappropriate antidiuretic hormone secretion (SIADH)
 * Thrombocytopenia
 * Prolonged bleeding time
 * Seizures
 * Mania
 * Neuroleptic malignant syndrome (NMS)
 * Serotonin syndrome
 * Akathisia/psychomotor restlessness
 * Urinary incontinence

Very rare (<0.01% incidence)

 * Anaphylaxis
 * QT prolongation
 * Ventricular fibrillation
 * Ventricular tachycardia (including torsades de pointes)
 * Pancreatitis
 * Blood dyscrasias (including agranulocytosis, aplastic anaemia, neutropenia and pancytopenia)
 * Elevated serum prolactin
 * Delirium
 * Extrapyramidal reactions (including dystonia and dyskinesia)
 * Tardive dyskinesia
 * Pulmonary eosinophilia
 * Erythema multiforme
 * Stevens–Johnson syndrome
 * Pruritus
 * Urticaria
 * Toxic epidermal necrolysis
 * Angle closure glaucoma