List of autoimmune diseases

This article provides a list of autoimmune diseases. These conditions, where the body's immune system mistakenly attacks its own cells, affect a range of organs and systems within the body. Each disorder is listed with the primary organ or body part that it affects and the associated autoantibodies that are typically found in people diagnosed with the condition. Each disorder is also categorized by its acceptance as an autoimmune condition into four levels: confirmed, probable, possible, and uncertain. This classification is based on the current scientific consensus and reflects the level of evidence supporting the autoimmune nature of the disorder. Lastly, the prevalence rate, specifically in the United States, is included to give a sense of how common each disorder is within the population.


 * Confirmed - Used for conditions that have strong, well-established evidence of autoimmune etiology.
 * Probable - Used for conditions where there is substantial evidence of autoimmune involvement, but the scientific consensus may not be as strong as for those in the 'confirmed' category.
 * Possible - Used for conditions that have some evidence pointing towards autoimmune involvement, but it's not yet clear or there is ongoing debate.
 * Uncertain - Used for conditions where the evidence of autoimmune involvement is limited or contested.

Integumentary system
The integumentary system, composed of the skin, hair, nails, and associated glands, serves as a protective barrier between the body and the environment. It also plays a critical role in regulating body temperature and maintaining fluid balance.

Reproductive system
The reproductive system is responsible for the production and regulation of sex hormones, the formation of germ cells, and the nurturing of fertilized eggs. In women, it includes structures such as ovaries, fallopian tubes, a uterus, and a vagina, while in men, it includes testes, vas deferens, seminal vesicles, prostate, and the penis. Autoimmune diseases of the reproductive system can affect both male and female fertility and reproductive health.

Muscular system
These autoimmune diseases are primarily associated with the muscles and neuromuscular function.

Autoimmune comorbidities
This list includes conditions that are not diseases, but symptoms or syndromes common to autoimmune disease.


 * Chronic fatigue syndrome
 * Complex regional pain syndrome
 * Eosinophilic esophagitis
 * Gastritis
 * POEMS syndrome
 * Raynaud's phenomenon
 * Primary immunodeficiency
 * Pyoderma gangrenosum

Non-autoimmune
At this time, there is not sufficient evidence to indicate that these diseases are caused by autoimmunity.