List of deputy prime ministers of Spain

The Deputy Prime Minister of Spain, Vice President of the Government or First Deputy Prime Minister (when there is more than one deputy prime minister) is the second highest position in the Government of Spain. Between 1840 and 1934 the title was Vice President of the Council of Ministers. Since its creation, there have been twenty-one deputy prime ministers.

List of officeholders
Office name:
 * Vice Presidency of the Council of Ministers (1840–1841; 1925–1931; 1933–1934)
 * Vice Presidency of the Government (1938–1939; 1962–1973; 1982–1995; 2011–2020)
 * First Vice Presidency of the Government (1974–1975; 1976; 1977–1979; 1981–1982; 1996–2011; 2020–present)
 * Vice Presidency of the Government for Defence Affairs (1975–1976)
 * First Vice Presidency of the Government for Defence Affairs (1976–1977)
 * First Vice Presidency of the Government, in charge of the Coordination of the Security and National Defence Affairs (1979–1981)
 * Vice Presidency of the Government for Economic Affairs (1982; 2011)