List of highways numbered 121

Route 121 or Highway 121 can refer to multiple roads:

Argentina

 * RN121-AR.svg National Route 121

Canada

 * NB 121.svg New Brunswick Route 121
 * Ontario 121.svg Ontario Highway 121
 * PEI Highway 121.svg Prince Edward Island Route 121

Costa Rica

 * CR RNS 121.svg National Route 121

Japan

 * Japanese National Route Sign 0121.svg Japan National Route 121

Nigeria

 * NGA road A121.svg A121 highway (Nigeria)

United States

 * US 121.svg U.S. Route 121 (proposed)
 * US 121 (1926).svg U.S. Route 121 (former)
 * Alabama 121.svg Alabama State Route 121 (former)
 * Arkansas 121.svg Arkansas Highway 121
 * California 121.svg California State Route 121
 * Colorado 121.svg Colorado State Highway 121
 * Connecticut Highway 121.svg Connecticut Route 121
 * Florida 121.svg Florida State Road 121
 * Alachua County 121A.svg County Road 121A (Alachua County, Florida)
 * Duval County Road 121 FL.svg County Road 121 (Duval County, Florida)
 * Georgia 121.svg Georgia State Route 121
 * HI-121.svg Hawaii Route 121
 * Illinois 121.svg Illinois Route 121
 * Indiana 121.svg Indiana State Road 121
 * K-121.svg K-121 (Kansas highway) (former)
 * Elongated circle 121.svg Kentucky Route 121
 * Louisiana 121.svg Louisiana Highway 121
 * Maine 121.svg Maine State Route 121
 * MD Route 121.svg Maryland Route 121
 * MA Route 121.svg Massachusetts Route 121
 * M-121.svg M-121 (Michigan highway)
 * MN-121.svg Minnesota State Highway 121
 * Hennepin County 121.svg County Road 121 (Hennepin County, Minnesota)
 * MO-121.svg Missouri Route 121
 * N-121.svg Nebraska Highway 121
 * Nevada 121.svg Nevada State Route 121
 * NH Route 121.svg New Hampshire Route 121
 * NH Route 121A.svg New Hampshire Route 121A
 * New Mexico 121.svg New Mexico State Road 121
 * NY-121.svg New York State Route 121
 * CR 121 jct.svg County Route 121 (Herkimer County, New York)
 * CR 121 jct.svg County Route 121 (Jefferson County, New York)
 * CR 121 jct.svg County Route 121 (Montgomery County, New York)
 * CR 121 jct.svg County Route 121 (Niagara County, New York)
 * CR 121 jct.svg County Route 121 (Seneca County, New York)
 * CR 121 jct.svg County Route 121 (Steuben County, New York)
 * Sullivan County Route 121 NY.svg County Route 121 (Sullivan County, New York)
 * NC 121.svg North Carolina Highway 121
 * OH-121.svg Ohio State Route 121
 * PA-121.svg Pennsylvania Route 121
 * Rhode Island 121.svg Rhode Island Route 121
 * South Carolina 121.svg South Carolina Highway 121
 * Texas 121.svg Texas State Highway 121
 * Toll Texas 121.svg former 121 Tollway (now Sam Rayburn Tollway)
 * Texas Loop 121.svg Texas State Highway Loop 121
 * Texas Spur 121.svg Texas State Highway Spur 121 (former)
 * Texas FM 121.svg Farm to Market Road 121
 * Utah SR 121.svg Utah State Route 121
 * Ellipse sign 121.svg Vermont Route 121
 * Virginia 121.svg Virginia State Route 121
 * Virginia 121.svg Virginia State Route 121 (1923-1926) (former)
 * Virginia 121.svg Virginia State Route 121 (1927-1928) (former)
 * Virginia 121.svg Virginia State Route 121 (1928-1933) (former)
 * WA-121.svg Washington State Route 121
 * WIS 121.svg Wisconsin Highway 121


 * Territories:
 * PR secondary 121.svg Puerto Rico Highway 121