List of highways numbered 381

The following highways are numbered 381:

Brazil

 * BR-381_jct.svg BR-381

Canada

 * Newfoundland and Labrador Route 381
 * Qc381.svg Quebec Route 381
 * Saskatchewan Highway 381

Japan

 * Japanese National Route Sign 0381.svg Japan National Route 381

United States

 * I-381.svg Interstate 381
 * Georgia 381.svg Georgia State Route 381 (former)
 * Elongated circle 381.svg Kentucky Route 381
 * MD Route 381.svg Maryland Route 381
 * NY-381.svg New York State Route 381 (former)
 * NC 381.svg North Carolina Highway 381
 * PA-381.svg Pennsylvania Route 381
 * Ellipse sign 381.svg Puerto Rico Highway 381
 * South Carolina 381.svg South Carolina Highway 381
 * Tennessee 381.svg Tennessee State Route 381
 * Virginia 381.svg Virginia State Route 381