List of highways numbered 385

Route 385, or Highway 385, may refer to:

Canada

 * NB 385.svg New Brunswick Route 385
 * Qc385.svg Quebec Route 385

Japan

 * Japanese National Route Sign 0385.svg Japan National Route 385

United States

 * I-385 (SC).svg Interstate 385
 * US 385.svg U.S. Route 385
 * Arkansas 385.svg Arkansas Highway 385
 * Florida 385.svg Florida State Road 385
 * Georgia 385.svg Georgia State Route 385
 * MD Route 385.svg Maryland Route 385 (former)
 * NY-385.svg New York State Route 385
 * New York State Route 385 (former)
 * OH-385.svg Ohio State Route 385
 * South Carolina 385.svg South Carolina Highway 385
 * Tennessee 385.svg Tennessee State Route 385
 * Texas:
 * Texas Loop 385.svg Texas State Highway Loop 385
 * Texas RM 385.svg Ranch to Market Road 385
 * Virginia 385.svg Virginia State Route 385
 * Territories:
 * PR secondary 385.svg Puerto Rico Highway 385