List of highways numbered 405

Route 405 or Highway 405 may refer to:

Canada

 * Manitoba secondary 405.svg Manitoba Provincial Road 405
 * NL Route 405.svg Newfoundland and Labrador Route 405
 * Ontario 405.svg Ontario Highway 405

Costa Rica

 * CR RNT 405.svg National Route 405

Japan

 * Japanese National Route Sign 0405.svg Japan National Route 405

United Kingdom

 * UK road A405.svg A405 road

United States

 * I-405.svg Interstate 405
 * Interstate 405 (California), a bypass of Los Angeles, California
 * Interstate 405 (Oregon), a bypass of Portland, Oregon
 * Interstate 405 (Washington), a bypass of Seattle, Washington
 * Florida:
 * Florida 405.svg Florida State Road 405
 * Brevard County 405.svg County Road 405 (Brevard County, Florida)
 * Georgia 405.svg Georgia State Route 405 (unsigned designation for Interstate 95)
 * MD Route 405.svg Maryland Route 405
 * New York:
 * NY-405.svg New York State Route 405 (former)
 * County Route 405 (Albany County, New York)
 * Erie County 405 NY.svg County Route 405 (Erie County, New York)
 * PA-405.svg Pennsylvania Route 405
 * Ellipse sign 405.svg Puerto Rico Highway 405
 * Virginia 405.svg Virginia State Route 405