List of highways numbered 81

Route 81 or Highway 81 may refer to:

International

 * Asian Highway 81
 * European route E81

Australia

 * Escort Way (New South Wales)
 * Mulligan Highway and Peninsula Developmental Road – Queensland State Route 81
 * (Victoria)

Canada

 * NL Route 81.svg Newfoundland and Labrador Route 81

India

 * NH81-IN.svg National Highway 81 (India)

Korea, South

 * National Route 81

Mexico

 * Mexican Federal Highway 81.png Mexican Federal Highway 81

Philippines

 * N81 (Philippines).svg N81 highway (Philippines)

United States

 * I-81.svg Interstate 81
 * I-81E (PA 1957).svg Interstate 81E (former)
 * I-81S (PA 1957).svg Interstate 81S (former)
 * US 81.svg U.S. Route 81
 * Alabama 81.svg Alabama State Route 81
 * Arizona 81.svg Arizona State Route 81 (former)
 * Arkansas 81.svg Arkansas Highway 81
 * California 81.svg California State Route 81
 * Connecticut Highway 81.svg Connecticut Route 81
 * Florida 81.svg Florida State Road 81
 * CR 81A jct.svg County Road 81A (Holmes County, Florida)
 * Georgia 81.svg Georgia State Route 81
 * ID-81.svg Idaho State Highway 81
 * Illinois 81.svg Illinois Route 81
 * Iowa 81.svg Iowa Highway 81
 * Circle sign 81.svg Kentucky Route 81
 * Louisiana 81.svg Louisiana Highway 81
 * Louisiana 81 (1955).svg Louisiana State Route 81 (former)
 * MD Route 81.svg Maryland Route 81 (former)
 * MA Route 81.svg Massachusetts Route 81
 * M-81.svg M-81 (Michigan highway)
 * Minnesota:
 * MNStar81.png Minnesota State Highway 81 (1934)
 * MN-81.svg Minnesota State Highway 81 (pre-1988)
 * MO-81.svg Missouri Route 81
 * MT-81.svg Montana Highway 81
 * N-81 1926.svg Nebraska Highway 81 (former)
 * Nevada 81.svg Nevada State Route 81 (former)
 * Circle sign 81.svg New Jersey Route 81
 * Bergen County 81.svg County Route 81 (Bergen County, New Jersey)
 * New Mexico 81.svg New Mexico State Road 81
 * NY-81.svg New York State Route 81
 * CR 81A jct.svg County Route 81A (Cayuga County, New York)
 * County Route 81C (Cayuga County, New York)
 * CR 81 jct.svg County Route 81 (Chautauqua County, New York)
 * Dutchess County Route 81 NY.svg County Route 81 (Dutchess County, New York)
 * Essex County Route 81 NY.svg County Route 81 (Essex County, New York)
 * CR 81 jct.svg County Route 81 (Madison County, New York)
 * CR 81 jct.svg County Route 81 (Montgomery County, New York)
 * CR 81 jct.svg County Route 81 (Oneida County, New York)
 * Rockland County Route 81 NY.svg County Route 81 (Rockland County, New York)
 * Suffolk County Route 81 NY.svg County Route 81 (Suffolk County, New York)
 * Sullivan County Route 81 NY.svg County Route 81 (Sullivan County, New York)
 * NC 81.svg North Carolina Highway 81
 * CR 81 jct.svg Country Road 81 (Richland County, North Dakota)
 * OH-81.svg Ohio State Route 81
 * Oklahoma State Highway 81A.svg Oklahoma State Highway 81A
 * PA-81.svg Pennsylvania Route 81 (former)
 * Rhode Island 81.svg Rhode Island Route 81
 * South Carolina 81.svg South Carolina Highway 81
 * SD 81.svg South Dakota Highway 81 (former)
 * Tennessee 81.svg Tennessee State Route 81
 * Tennessee State Route 81A (former)
 * Texas 81.svg Texas State Highway 81
 * Texas Loop 81.svg Texas State Highway Loop 81 (former)
 * Texas FM 81.svg Farm to Market Road 81
 * Utah SR 81.svg Utah State Route 81
 * Virginia 81.svg Virginia State Route 81 (former)
 * WV-81.svg West Virginia Route 81 (1925–1941) (former)
 * WV-81.svg West Virginia Route 81 (1960–1961) (former)
 * WIS 81.svg Wisconsin Highway 81


 * Territories:
 * Circle sign 81.svg U.S. Virgin Islands Highway 81