List of opioids

This is a list of opioids, opioid antagonists and inverse agonists.

Crude opiate extracts whole opium products

 * B&O Supprettes
 * Diascordium
 * Dover's powder
 * Kendal Black Drop
 * Laudanum
 * Mithridate
 * Opium
 * Polish heroin (Compote, Kompot)
 * Paregoric
 * Poppy straw concentrate
 * Poppy tea
 * Smoking opium
 * Theriac

Opium alkaloids

 * Codeine
 * Morphine
 * Oripavine
 * Pseudomorphine
 * Thebaine

Alkaloid salts mixtures

 * Pantopon
 * Papaveretum (Omnopon)
 * Tetrapon

Morphine family

 * 14-Hydroxymorphine
 * 2,4-Dinitrophenylmorphine
 * 6-Methyldihydromorphine
 * 6-Methylenedihydrodesoxymorphine
 * 6-Acetyldihydromorphine
 * Azidomorphine
 * Chlornaltrexamine
 * Chloroxymorphamine
 * Desomorphine (dihydrodesoxymorphine)
 * Dihydromorphine
 * Ethyldihydromorphine
 * Hydromorphinol
 * Methyldesorphine
 * Morphine methylbromide
 * N-Phenethylnordesomorphine
 * N-Phenethyl-14-ethoxymetopon
 * N-Phenethylnormorphine
 * 6-Nicotinoyldihydromorphine (metabolite of nicodicodeine)
 * RAM-378
 * Ro-1539

3,6-diesters of morphine

 * Acetylpropionylmorphine
 * 3,6-Dibutanoylmorphine
 * Diacetyldihydromorphine (dihydroheroin, acetylmorphinol)
 * Dibutyrylmorphine
 * Dibenzoylmorphine (first designer drug)
 * Diformylmorphine
 * Dipropanoylmorphine
 * Heroin (diacetylmorphine)
 * Nicomorphine

Codeine-dionine family

 * 6-Monoacetylcodeine
 * Benzylmorphine
 * Codeine methylbromide
 * Desocodeine
 * Dimethylmorphine (6-O-Methylcodeine)
 * Ethyldihydromorphine
 * Methyldihydromorphine (dihydroheterocodeine)
 * Ethylmorphine (dionine)
 * Heterocodeine
 * Isocodeine
 * Pholcodine (morpholinylethylmorphine)
 * Myrophine
 * Thebacon
 * Transisocodeine

Morphinones and morphols

 * 14-Cinnamoyloxycodeinone
 * 14-Ethoxymetopon
 * 14-Methoxymetopon
 * 14-Phenylpropoxymetopon
 * 3-Acetyloxymorphone
 * 3,14-Diacetyloxymorphone
 * 7-Spiroindanyloxymorphone
 * 8,14-Dihydroxydihydromorphinone
 * Acetylcodone
 * Acetylmorphone
 * α-hydrocodol (=dihydrocodeine, )
 * Benzhydrocodone
 * Bromoisopropropyldihydromorphinone cas?
 * Codeinone
 * Codoxime
 * Conorfone (codorphone)
 * IBNtxA
 * Thebacon (acetyldihydrocodeinone, dihydrocodeinone enol acetate)
 * Hydrocodone
 * Hydromorphone
 * Hydroxycodeine
 * Metopon (=methyldihydromorphinone)
 * Morphenol
 * Morphinone
 * Morphol
 * N-Phenethyl-14-ethoxymetopon
 * Noroxymorphone
 * Oxycodone
 * Oxymorphol
 * Oxymorphone
 * Pentamorphone
 * Semorphone

Morphides

 * α-Chlorocodide (= chlorocodide)
 * β-Chlorocodide
 * α-Chloromorphide (= chloromorphide)
 * Bromocodide
 * Bromomorphide
 * Chlorodihydrocodide
 * Chloromorphide
 * Codide

Dihydrocodeine series

 * 14-Hydroxydihydrocodeine
 * Acetyldihydrocodeine
 * Dihydrocodeine
 * Dihydrodesoxycodeine (desocodeine)
 * Dihydroisocodeine
 * Nicocodeine
 * Nicodicodeine

Nitrogen morphine derivatives

 * 1-Nitrocodeine cas?
 * Codeine-N-oxide
 * Morphine-N-oxide

Hydrazones

 * Oxymorphazone

Halogenated morphine derivatives

 * 1-Bromocodeine
 * 1-Chlorocodeine
 * 1-Iodomorphine

Active opiate metabolites

 * Codeine-6-glucuronide
 * Codeine-N-oxide (genocodeine)
 * Heroin-7,8-oxide
 * Morphine-6-glucuronide
 * 3-Monoacetylmorphine
 * 6-Monoacetylmorphine
 * Morphine-N-oxide (genomorphine)
 * Naltrexol
 * Norcodeine
 * Normorphine

Morphinan series

 * 3-Hydroxymorphinan
 * 4-Chlorophenylpyridomorphinan
 * Cyclorphan
 * Levargorphan
 * Levorphanol
 * Levophenacylmorphan
 * Levomethorphan
 * Methorphan (racemethorphan)
 * Morphanol (racemorphanol)
 * Norlevorphanol
 * N-Methylmorphinan
 * Oxilorphan
 * Phenomorphan
 * Proxorphan
 * Ro4-1539
 * Stephodeline Xorphanol

Others

 * 1-Nitroaknadinine * 14-episinomenine
 * 5,6-Dihydronorsalutaridine
 * 6-Keto Nalbuphine
 * Aknadinine
 * Butorphanol
 * Cephakicine
 * Cephasamine
 * Cyprodime
 * Drotebanol
 * Fenfangjine G
 * Ketorfanol
 * Nalbuphine
 * Nalbuphone
 * Tannagine

Benzomorphans

 * 5,9 alpha-diethyl-2-hydroxybenzomorphan (5,9-DEHB)
 * 8-Carboxamidocyclazocine (8-CAC)
 * Alazocine
 * Anazocine
 * Bremazocine
 * Butinazocine
 * Carbazocine
 * Cogazocine
 * Cyclazocine
 * Dezocine
 * Eptazocine
 * Etazocine
 * Ethylketazocine
 * Fedotozine
 * Fluorophen
 * Gemazocine
 * Ibazocine
 * Ketazocine
 * Metazocine
 * Moxazocine
 * Pentazocine
 * Phenazocine
 * Quadazocine
 * SKF-10047


 * Tonazocine
 * Volazocine
 * Zenazocine

Pethidines (meperidines)

 * 4-Fluoropethidine
 * Allylnorpethidine
 * Anileridine
 * Benzethidine
 * Carperidine
 * Difenoxin
 * Diphenoxylate
 * Etoxeridine (carbetidine)
 * Furethidine
 * Hydroxypethidine (bemidone)
 * Morpheridine
 * Meperidine-N-oxide
 * Oxpheneridine (carbamethidine)
 * Pethidine (meperidine)
 * Pethidine intermediate A
 * Pethidine intermediate B (norpethidine)
 * Pethidine intermediate C (pethidinic acid)
 * Pheneridine
 * Phenoperidine
 * Piminodine
 * Properidine (ipropethidine)
 * Sameridine

Prodines

 * Allylprodine
 * (α/β)-Meprodine
 * Desmethylprodine (MPPP)
 * PEPAP
 * (α/β)-Prodine
 * Prosidol
 * Trimeperidine (promedol)

Ketobemidones

 * Acetoxyketobemidone
 * Droxypropine
 * Ketobemidone
 * Methylketobemidone
 * Propylketobemidone

Others

 * Alvimopan
 * Loperamide
 * LS-115509
 * Picenadol

Amidones

 * Dextromethadone
 * Dipipanone
 * Isomethadone=
 * Levoisomethadone
 * Levomethadone
 * Methadone
 * Methadone intermediate
 * Normethadone
 * Norpipanone
 * Phenadoxone (heptazone)

Methadols

 * Acetylmethadol
 * Alphaacetylmethadol
 * Alphamethadol
 * Betacetylmethadol
 * Betamethadol
 * Dimepheptanol (racemethadol)
 * Isomethadol
 * Levacetylmethadol
 * Noracymethadol

Moramides

 * Desmethylmoramide
 * Dextromoramide
 * Levomoramide
 * Moramide intermediate
 * Racemoramide

Thiambutenes

 * Diethylthiambutene
 * Dimethylthiambutene
 * Ethylmethylthiambutene
 * Piperidylthiambutene
 * Pyrrolidinylthiambutene
 * Thiambutene

Phenalkoxams

 * Dextropropoxyphene (propoxyphene)
 * Dimenoxadol
 * Dioxaphetyl butyrate
 * Levopropoxyphene
 * Norpropoxyphene
 * Pyrroliphene

Ampromides

 * Diampromide
 * Phenampromide
 * Propiram

Others

 * Embutramide
 * IC-26
 * Isoaminile
 * Lefetamine
 * R-4066

Anilidopiperidines



 * 3-Allylfentanyl
 * 3-Methylfentanyl
 * 3-Methylthiofentanyl
 * 4-Phenylfentanyl
 * Alfentanil
 * α-Methylacetylfentanyl
 * α-Methylfentanyl
 * α-Methylthiofentanyl
 * Benzylfentanyl
 * β-hydroxyfentanyl
 * β-hydroxythiofentanyl
 * β-Methylfentanyl
 * Brifentanil
 * Butyrfentanyl
 * Carfentanil
 * Fentanyl
 * Lofentanil
 * N-Methylcarfentanil
 * Mirfentanil
 * Ocfentanil
 * Ohmefentanyl
 * Parafluorofentanyl
 * Phenaridine
 * R-30490
 * Remifentanil
 * Sufentanil
 * Thenylfentanyl
 * Thiofentanyl
 * Trefentanil
 * Trefentanil

Oripavine derivatives



 * 7-PET
 * Acetorphine
 * Alletorphine (N-allyl-noretorphine)
 * BU-48
 * Buprenorphine
 * Buprenorphine-3-glucuronide
 * Cyprenorphine
 * Dihydroetorphine
 * Etorphine
 * Homprenorphine
 * 18,19-Dehydrobuprenorphine (HS-599)
 * N-cyclopropylmethylnoretorphine
 * Nepenthone
 * Norbuprenorphine
 * Norbuprenorphine-3-glucuronide
 * Thevinone
 * Thienorphine

Phenazepanes

 * Ethoheptazine
 * Meptazinol
 * Metheptazine
 * Metethoheptazine
 * Proheptazine

Pirinitramides

 * Bezitramide
 * Piritramide

Benzimidazoles

 * Clonitazene
 * Etonitazene
 * Isotonitazene
 * Metonitazene

Indoles

 * 18-Methoxycoronaridine
 * 7-Acetoxymitragynine
 * 7-Hydroxymitragynine
 * ψ-Akuammigine
 * Akuammidine
 * Akuammine
 * Coronaridine
 * Eseroline
 * Hodgkinsine
 * Ibogaine
 * Mitragynine
 * Mitragynine pseudoindoxyl
 * Noribogaine
 * Pericine
 * Pseudoakuammigine

Beta-Amino Ketones

 * 3-(dimethylamino)-2,2-dimethyl-1-phenylpropan-1-one

Diphenylmethylpiperazines

 * BW373U86
 * DPI-221
 * DPI-287
 * DPI-3290
 * SNC-80
 * AZD-2327

Dynorphins

 * Big dynorphin
 * Dynorphin A
 * Dynorphin B
 * Leumorphin

Endomorphins

 * Endomorphin-1
 * Endomorphin-2

Endorphins

 * α-Endorphin
 * β-Endorphin
 * γ-Endorphin
 * α-Neoendorphin
 * β-Neoendorphin

Enkephalins

 * DADLE
 * DAMGO
 * Deltorphin
 * Met-enkephalin
 * Leu-enkephalin

Propeptides

 * Proenkephalin
 * Proendorphin
 * Proopiomelanocortin

Others / unknown

 * Adrenorphin
 * Amidorphin
 * Biphalin
 * Casokefamide
 * Casomorphins
 * Cytochrophin-4
 * DALDA (Tyr-D-Arg-Phe-Lys-NH2)
 * Deltorphin I
 * Deltorphin II
 * Deprolorphin
 * Dermorphin
 * DPDPE
 * Frakefamide
 * Gliadorphin
 * Gluten exorphins
 * Hemorphin-4
 * Metkefamide
 * Morphiceptin
 * Nociceptin
 * Octreotide
 * Opiorphin
 * Rubiscolin
 * Soymorphins
 * Spinorphin
 * TRIMU 5
 * Tynorphin
 * Valorphin
 * Zyklophin

Others

 * 3-(3-Methoxyphenyl)-3-ethoxycarbonyltropane
 * AD-1211
 * AH-7921
 * Axomadol
 * Azaprocin
 * BDPC
 * Bisnortilidine
 * BRL-52537
 * Bromadol
 * Bromadoline
 * Ciprefadol
 * Ciramadol
 * Doxpicomine
 * Enadoline
 * Faxeladol
 * GR-89696
 * Herkinorin
 * ICI-199,441
 * ICI-204,448
 * Ketamine
 * KNT-42
 * LPK-26
 * Lufuradom
 * Metofoline
 * MT-45
 * Desmethylclozapine
 * Nexeridine
 * NNC 63-0532
 * Nortilidine
 * O-Desmethyltramadol
 * Phenadone
 * Phencyclidine
 * Prodilidine
 * Profadol
 * Ro64-6198
 * Salvinorin A
 * Salvinorin B ethoxymethyl ether
 * Salvinorin B methoxymethyl ether
 * SB-612,111
 * SC-17599
 * RWJ-394,674
 * TAN-67
 * Tapentadol
 * Thiobromadol (C-8813)
 * Tifluadom
 * Tilidine
 * Tramadol
 * Trimebutine
 * U-47700
 * U-50,488
 * U-69,593
 * Viminol
 * 1-(4-Nitrophenylethyl)piperidylidene-2-(4-chlorophenyl)sulfonamide (W-18)

Opioid antagonists and inverse agonists

 * 4-Caffeoyl-1,5-quinide
 * 5'-Guanidinonaltrindole
 * β-Funaltrexamine
 * 6β-Naltrexol
 * 6β-Naltrexol-d4
 * Alvimopan
 * AT-076
 * Binaltorphimine
 * BU09059
 * Buprenorphine
 * Chlornaltrexamine
 * Clocinnamox
 * Cyclazocine
 * Cyprodime
 * Diacetylnalorphine
 * Diprenorphine (M5050)
 * Fedotozine
 * ICI-174864
 * J-113,397
 * JDTic
 * JTC-801
 * Levallorphan
 * LY-2456302
 * LY-255582
 * Methocinnamox
 * Methylnaltrexone
 * ML350
 * Naldemedine
 * Nalfurafine
 * Nalmefene
 * Nalmexone
 * Nalodeine (N-allylnorcodeine)
 * Naloxazone
 * Naloxegol
 * Naloxol
 * Naloxonazine
 * Naloxone
 * Naloxone benzoylhydrazone
 * Nalorphine
 * Naltrexone
 * Naltriben
 * Naltrindole
 * Norbinaltorphimine
 * Oxilorphan
 * PF-4455242
 * S-allyl-3-hydroxy-17-thioniamorphinan (SAHTM)
 * Samidorphan
 * SR-16430

Biased ligands

 * 6'-Guanidinonaltrindole
 * 7-Hydroxymitragynine
 * Herkinorin
 * ICI-199,441
 * Noribogaine
 * Oliceridine
 * RB-64
 * TRV734

Receptor heteromer targeting ligands

 * 6'-GNTI (δ-κ)
 * CYM-51010 (δ-μ)
 * NNTA (κ-μ)
 * IBNtxA (μ1G-NOP)

Uncategorized opioids

 * ADL-5859
 * Alimadol
 * Amentoflavone
 * Anilopam +HCl
 * Asimadoline
 * Cyproterone acetate
 * FE 200665
 * Fedotozine
 * HZ-2
 * Kolokol-1
 * Matrine
 * MCOPPB
 * Menthol
 * MT-7716
 * Nalfurafine
 * Nalorphine
 * Nalorphine dinicotinate
 * PZM21
 * Proglumide
 * Ro65-6570
 * SoRI-9409
 * Spiradoline
 * SR-8993
 * SR-16435

Combination drug formulations containing opioids

 * Buprenorphine/naloxone
 * Buprenorphine/samidorphan (ALKS-5461)
 * Co-codamol (codeine phosphate/paracetamol)
 * Co-codaprin (codeine phosphate/aspirin)
 * Co-dydramol (dihydrocodeine tartrate/paracetamol)
 * Co-proxamol (dextropropoxyphene/paracetamol)
 * Fentanyl/fluanisone
 * Hydrocodone/ibuprofen
 * Hydrocodone/paracetamol
 * Loperamide/simethicone
 * Morphine/naltrexone
 * Naltrexone/bupropion
 * Oxycodone/aspirin
 * Oxycodone/naloxone
 * Oxycodone/paracetamol