List of tallest buildings in Columbia, South Carolina

The history of high-rise buildings in Columbia, South Carolina began with the construction of the National Loan and Exchange Bank Building in 1903. A decade later, the Palmetto Building was built across the street, becoming the tallest in the state. During the 1970s and 80s, Columbia experienced a building boom, which brought economic growth to the region, including several of the city's tallest buildings.

The following table shows the fifteen tallest buildings in Columbia, South Carolina.