M100

M100 or M-100 may refer to:


 * M-100 (Michigan highway), a north–south state trunkline highway in the U.S. state of Michigan
 * M100 (Cape Town), a metropolitan route near Cape Town, South Africa
 * M-100 (rocket), a two-stage Soviet sounding rocket
 * M-100 (explosive), a pyrotechnic device
 * M100, the magnetoencephalographic equivalent to the N100 large, negative-going evoked potential measured by electroencephalography
 * Messier 100, a grand design spiral galaxy
 * Miles Student (M.100), a lightweight trainer aircraft
 * Palm m100 series, a popular lower cost version of the Palm Pilot
 * M100 (New York City bus), a New York City Bus route in Manhattan
 * Effa M100, the Brazilian name for the Changhe Ideal automobile
 * M100, the second version of the Jeep trailer
 * M100 Elan, a model of the Lotus Elan automobile
 * Mercedes-Benz M100 engine, a 6.3/6.9 liter SOHC V8 automobile engine
 * TRS-80 Model 100, an early portable computer
 * Canon EOS M100, an mirrorless camera from Canon
 * Mitsubishi SpaceJet M100, a regional jet aircraft
 * HKL Class M100, a metro train of Helsinki Metro
 * M100 (Cape Town), a Metropolitan Route in Cape Town, South Africa

In athletics:
 * Masters athletics, an age group for athletes aged 35+