M104

M104 or M-104 may refer to:


 * Sombrero Galaxy, called M104 by Messier number
 * M104 group of galaxies
 * HMS Walney (M104), a British warship
 * M104 Wolverine, a military armored bridge
 * M104 155mm Cartridge, a U.S. Army chemical artillery shell
 * M104 (New York City bus), a New York City Bus route in Manhattan
 * Mercedes-Benz M104 engine
 * M-104 highway (Michigan), a road in the United States
 * a Y-chromosome mutation, also called P22