MGB

MGB may refer to:
 * Mass General Brigham, a Massachusetts-based integrated health care system and hospital-based research enterprise
 * Mathematical Gymnasium Belgrade (Matematička Gimnazija), an elementary and high school for gifted students in Serbia
 * Magandang Gabi, Bayan, a news program in the Philippines
 * Matterhorn Gotthard Bahn, a railroad operating in the Swiss Alps
 * Matthew Good Band, a Canadian group
 * Medial geniculate nucleus, or medial geniculate body, a subnucleus of the thalamus in the brain
 * Medium Girder Bridge, a modular, military bridge
 * MG MGB, a sports car produced by the British Motor Corporation and its successors from 1962 to 1980
 * Mines and Geosciences Bureau, a government agency in the Philippines
 * Ministry for State Security (Soviet Union) (Ministerstvo Gosudarstvennoi Bezopasnosti), a predecessor of the KGB
 * Motor Gun Boat, a fast attack boat armed with cannons and guns, as opposed to the Motor Torpedo Boat
 * Mount Gambier Airport, an airport servicing the Mount Gambier region which uses the IATA code MGB
 * Game Boy Pocket (product code MGB-001) and Game Boy Light (product code MGB-101), portable gaming devices by Nintendo