MI-6 (disambiguation)

MI6 is the United Kingdom's Secret Intelligence Service.

MI-6 or MI6 may also refer to:
 * AMD's MI6, a brand of deep learning oriented Graphics Processing Units, see Radeon Instinct
 * Mil Mi-6, a Soviet built transport helicopter
 * Michigan's 6th congressional district
 * M-6 (Michigan highway)
 * MI6.co.uk, former website of the media-website MI6-HQ.com
 * Mission: Impossible – Fallout, a 2018 spy-thriller film starring Tom Cruise
 * Xiaomi Mi 6, a smartphone developed by Xiaomi
 * Return to Monkey Island (also known as Monkey Island 6), videogame