MPU

MPU may refer to:

Science and technology

 * Medical-grade polyurethane, a polyurethane used in medicine; for example see Vas-occlusive contraception

Computing

 * Memory protection unit, for example in the ARM Cortex-M
 * Microprocessor unit, a central processing unit when referring to digital signal processors
 * MPU-401 (MIDI Processing Unit), an obsolete standard for MIDI interfaces for personal computers
 * Multi-core processing unit, a system made of two or more independent cores; See History of general-purpose CPUs

Other uses

 * Mabua Airstrip (IATA code: MPU), an airport in Papua New Guinea
 * Melbourne Poets Union, a forerunner of Australian Poetry and later reincarnated under the same name
 * Minimum publishable unit, the smallest piece of a scientist's results that can be made into an academic paper
 * Mișcarea Politică Unirea, a Moldovan political party
 * Myanmar Payment Union, a Myanmar financial services corporation
 * Medical-psychological assessment in Germany, called MPU for Medizinisch-Psychologische Untersuchung
 * Missing Persons Unit, a police unit to locate missing persons
 * Missing Persons Unit, an Australian TV documentary series
 * Alert: Missing Persons Unit, an American TV fiction series