MSPA

MSPA may refer to:
 * Maritime Security Patrol Area, patrol zone in the Gulf of Aden, between Somalia and Yemen
 * Migrant and Seasonal Agricultural Workers Protection Act, United States law
 * Mississippi Association of Independent Schools, formerly the Mississippi Private School Association
 * MspA porin, protein produced by mycobacteria
 * Member, Society of Pension Actuaries; see American Society of Pension Professionals and Actuaries
 * MS Paint Adventures, a group of web-comics by Andrew Hussie
 * Multiple Spacecraft Per Aperture, shared antenna dish usage. see NASA Deep Space Network