MSSP

MSSP may refer to:
 * Managed Security Service Provider, who provides security services for companies
 * Microsoft Smooth Streaming Protocol, a computer networking protocol designed to support adaptive media streaming
 * Mobile Service Switching Point, see Service Switching Point
 * Medicare Shared Savings Program, established by section 3022 of the Affordable Care Act
 * Master Synchronous Serial Port, a module of a PIC microcontroller that is used for communication with other peripherals
 * Missionary Society of St Paul (Malta)