Madonna and Child with Two Saints

Madonna and Child with Two Saints may refer to:
 * Madonna and Child with Two Saints (Bicci) (c.1475), a tempera and gold on panel altarpiece in the Montreal Museum of Fine Arts
 * Madonna and Child with Two Saints (Gentile da Fabriano) (c.1390–1395), a tempera and gold on panel painting in the Pinacoteca Malaspina, Pavia
 * Madonna and Child with Two Saints (Lotto) (1508), an oil-on-panel painting in the Borghese Gallery, Rome
 * Madonna and Child with Two Saints (Perugino) (c.1495), a tempera on panel painting in the Kunsthistorisches Museum, Vienna
 * Madonna and Child with Two Saints (Pisanello) (c.1445), a panel painting in the National Gallery, London
 * Madonna and Child with Two Saints (Signorelli) (c.1492–1493), a tempera on panel tondo painting in the Palazzo Corsini, Florence