Main Street station

Main Street station may refer to:

Canada

 * Main Street station (Toronto), a subway station in Toronto, Ontario, Canada
 * Main Street–Science World station, a SkyTrain station in Vancouver, British Columbia, Canada

United Kingdom

 * Main Street railway station (Glasgow), in Glasgow, Scotland

United States

 * Main Street station (SEPTA), in Norristown, Pennsylvania, United States
 * Main Street Station Hotel and Casino and Brewery, in Las Vegas, Nevada, United States
 * Alma School/Main Street station, in Mesa, Arizona, United States
 * Center/Main Street station, in Mesa, Arizona, United States
 * Downers Grove Main Street station, in Downers Grove, Illinois, United States
 * Evanston Main Street station, in Evanston, Illinois, United States
 * Flushing–Main Street (IRT Flushing Line), in Queens, New York, United States
 * Flushing–Main Street (LIRR station), in Queens, New York, United States
 * Mesa Drive/Main Street station, in Mesa, Arizona, United States
 * Richmond Main Street Station, in Richmond, Virginia, United States
 * Southeast Main Street MAX Station, in Portland, Oregon, United States
 * Sycamore/Main Street station, in Mesa, Arizona, United States