Mainframe (disambiguation)

A mainframe computer is a type of large data processing system.

Mainframe may also refer to:


 * Mainframe Studios, a Canadian computer animation company founded as Mainframe Entertainment

Fictional entities

 * Mainframe (comics), several Marvel Comics characters
 * Mainframe (G.I. Joe), a character in the G.I. Joe universe
 * Mainframe, a character from the game Gunman Chronicles
 * Mainframe, the city in the animated series ReBoot
 * Tina "Mainframe" Cassidy, a character from the animated TV series COPS
 * Mainframe, a character in Gene Wolfe's series of novels The Book of the Long Sun