Mannose-1-phosphate guanylyltransferase (GDP)

In enzymology, a mannose-1-phosphate guanylyltransferase (GDP) is an enzyme that catalyzes the chemical reaction


 * GDP + alpha-D-mannose 1-phosphate $$\rightleftharpoons$$ phosphate + GDP-mannose

Thus, the two substrates of this enzyme are GDP and alpha-D-mannose 1-phosphate, whereas its two products are phosphate and GDP-mannose.

This enzyme belongs to the family of transferases, specifically those transferring phosphorus-containing nucleotide groups (nucleotidyltransferases). The systematic name of this enzyme class is GDP:alpha-D-mannose-1-phosphate guanylyltransferase. This enzyme participates in fructose and mannose metabolism.

Other common names

 * GDP mannose phosphorylase
 * Mannose 1-phosphate (guanosine diphosphate) guanylyltransferase
 * GDP mannose phosphorylase
 * GDP-mannose 1-phosphate guanylyltransferase
 * Guanosine diphosphate-mannose 1-phosphate guanylyltransferase
 * Guanosine diphosphomannose phosphorylase
 * Mannose 1-phosphate guanylyltransferase
 * GDP:D-mannose-1-phosphate guanylyltransferase