Mannosylglycoprotein endo-beta-mannosidase

Mannosylglycoprotein endo-beta-mannosidase (, endo-beta-mannosidase) is an enzyme. This enzyme catalyses the following chemical reaction:


 * Hydrolysis of the alpha-D-mannosyl-(1->6)-beta-D-mannosyl-(1->4)-N-acetyl-beta-D-glucosaminyl-(1->4)-N-acetyl-beta-D-glucosaminyl sequence of glycoprotein to alpha-D-mannosyl-(1->6)-D-mannose and N-acetyl-beta-D-glucosaminyl-(1->4)-N-acetyl-beta-D-glucosaminyl sequences

The substrate group is a substituent on N-4 of an asparagine residue in the glycoprotein.