Manuel Vargas

Manuel Vargas may refer to:


 * Manuel Vargas (footballer) (born 1991), Panamanian footballer
 * Manuel Vargas (boxer) (born 1981), professional boxer
 * Manuel Vargas (singer), lead member of the Mariachi Sangre Mexicana
 * Manuel Cepeda Vargas (1930–1994), lawyer and Senator of Colombia
 * Manuel Francisco de Vargas (1849-1921), Portuguese engineer and politician