Manuel Villegas

Manuel Villegas may refer to:


 * Manuel Delgado Villegas (1943–1998), Spanish serial killer
 * Manuel Villegas (golfer) (born 1984), Colombian golfer
 * Manuel Villegas (swimmer) (1908–?), Mexican swimmer
 * Manuel Villegas Piñateli (died 1752), member of the Royal Spanish Academy