Margaret Butler

Margaret Butler may refer to:
 * Lady Margaret Butler (died 1539), Irish noblewoman
 * Margaret F. Butler (1861–1931), American physician and professor
 * Margaret FitzGerald, Countess of Ormond (died 1542), Irish noblewoman with the married name Butler
 * Margaret K. Butler (1924–2013), American mathematician who specialized in early computer software
 * Margaret Butler (sculptor) (1883–1947), New Zealand sculptor