Margaret Hughes (disambiguation)

Margaret Hughes (c. 1630–1719) was an English actress; mistress of Prince Rupert of the Rhine.

Margaret Hughes may also refer to:


 * Margaret Hughes (bowls), lawn bowler from Zambia
 * Margaret Hughes (Los Angeles) (1826–1915), first woman member of the Los Angeles City Board of Education
 * Margaret Hughes (sportswriter) (1919–2005), English sportswriter
 * Margaret Hughes, Miss Australia 1949
 * Margaret Hughes, a character in The Wiser Sex