Mario Sergio

Mario Sergio may refer to:


 * Mário Sérgio (actor, born 1929), Brazilian actor
 * Mario Sergio (politician) (born 1940), Canadian politician
 * Mário Sérgio (footballer, born 1950) (1950–2016), Brazilian football manager and former midfielder
 * Mário Sérgio (footballer, born 1977), Brazilian football midfielder
 * Mário Sérgio (footballer, born 1981), Portuguese football right-back
 * (born 1983), Colombian footballer
 * Mário Sérgio (footballer, born 1992), Brazilian football defender
 * Mário Sérgio (footballer, born 1995), Brazilian football forward