Mark Spencer

Mark Spencer may refer to:
 * Mark Spencer (botanist), British forensic botanist
 * Mark Spencer (computer engineer) (born 1977), American computer engineer
 * Mark Spencer (guitarist) (born 1957), American guitarist
 * Mark Spencer (British politician) (born 1970), British Member of Parliament for Sherwood
 * Mark Spencer (New York politician) (1787–1859), New York politician
 * Mark G. Spencer (born 1967), Canadian historian