Mary Anna

Mary Anna may refer to:


 * Mary Anna Custis Lee (1807–1873), American wife of Robert E. Lee, slave owner, and socialite
 * Mary Anna Day (1852–1924), American botanist and librarian
 * Mary Anna Draper (1839–1914), American astronomical photographer and researcher
 * Mary Anna Henry (1834–1903), American diarist
 * Mary Anna Jackson (1831–1915), American second wife, and subsequently widow, of Stonewall Jackson
 * Mary Anna Marten (1929–2010), English aristocrat and landowner
 * Mary Anna Needell (1830–1922), English novelist
 * Mary Anna Wyall (1922–2017), American aviator