Mary Bethune (disambiguation)

Mary Bethune may refer to:
 * Mary Bethune Abbott (1823–1898), wife of John Abbott, Prime Minister of Canada
 * Mary Beaton or Bethune (1543–1598), Scottish noblewoman and attendant of Mary, Queen of Scots
 * Mary McLeod Bethune (1875–1955), African-American educator, philanthropist and civil rights activist