Mary Byrne

Mary Byrne may refer to:
 * Mary Byrne (mayor) (1917–2004), mayor of Galway
 * Mary Byrne (singer) (born 1959), Irish singer, 2010 The X Factor UK contestant
 * Mary Ann Byrne (1854–1894), Irish nationalist
 * Mary Elizabeth Byrne (1880–1931), Irish author and linguist
 * Mary Freeman Byrne (1886–1961), American author
 * Mary Gregg Byrne (born 1951), American portraitist, illustrator, and landscape artist
 * Mary Byrne (witness), Irish woman considered to be the chief witness of the apparition at Knock, County Mayo
 * Mary Martha Byrne (born 1969), American actress
 * Mary Rose Byrne (born 1979), Australian actress
 * Mary Green (painter) (1766–1845), British painter born Mary Byrne