Mary Isabella

Mary Isabella may refer to:
 * Mary Isabella Hales Horne (1818–1905), English-born American Mormon leader
 * Mary Isabella Langrishe (1864–1939), Irish tennis player
 * Mary Isabella Lee (1871–1939), New Zealand servant, dressmaker, coalminer, and homemaker
 * Mary Isabella Macleod (1852–1933), Canadian pioneer
 * Mary Isabella Shields, birth name of Mamie Shields Pyle (1866–1949), American women's suffrage leader
 * Mary Isabella Taylor, birth name of Peta Taylor (1912–1989), English cricketer
 * Mary Isabella Wickenhauser (1910–1995), American actress