McIsaac

McIsaac is a surname. Notable people with the surname include:


 * Alan McIsaac (born 1954), Canadian politician
 * Angus McIsaac (1842–1902), Canadian politician
 * Billy McIsaac (born 1949), Scottish musician
 * Cliff McIsaac (1930–2006), Canadian politician
 * Colin Francis McIsaac (1854–1927), Canadian politician
 * Hazel McIsaac (1933–2012), Canadian politician
 * Hilary McIsaac (1820–1901), Canadian politician
 * James McIsaac (1854–1927), Canadian politician
 * John L. McIsaac (1870–1941), Canadian politician
 * Justin McIsaac (born 1978), American wrestler
 * Shona McIsaac (born 1960), Scottish politician
 * Tai McIsaac (born 1975), Australian rugby union player