Mesoamerica (disambiguation)

Mesoamerica (lit. "mid/middle America") is a historical region and cultural area in southern North America and most of Central America.

Mesoamerica(n) or Meso-America(n) may also refer to:
 * Mesoamerican language area, a linguistic area or sprachbund comprising numerous indigenous languages in Mesoamerica that exhibit certain similarities
 * Mesoamerican Barrier Reef System, system of coral reefs in the Caribbean Sea along the coast of Yucatán and Central America
 * Mesoamerican Biological Corridor, a biodiversity conservation initiative formed in 1997 to interconnect a number of protected areas in Mesoamerica
 * Mesoamerican region, a trans-national economic territory comprising Central America and the southeastern states of Mexico
 * Universidad Mesoamericana, a university in Guatemala with campuses in Guatemala City and Quetzaltenango