Methade

Methade, or 6-(dimethylamino)-4,4-diphenylheptane, is the parent compound of the methadone and methadol series of opioid analgesics:

Derived from the chemical structure of methadone, various analogs and derivatives have been synthesized and developed to enhance its therapeutic properties and minimize potential side effects. Methadone itself is a synthetic opioid that exhibits potent analgesic properties, making it effective in relieving moderate to severe pain. It acts on the central nervous system, specifically targeting opioid receptors in the brain and spinal cord to alleviate pain signals.

One of the notable applications of methadone is in the treatment of opioid addiction. It has been widely used as a substitution therapy for individuals addicted to opioids, such as heroin or prescription painkillers. Methadone treatment helps to reduce withdrawal symptoms and cravings, allowing individuals to stabilize their lives and gradually taper off opioids under medical supervision.

The methadone series of opioids, which share a structural similarity to methadone, have been developed with the aim of improving therapeutic efficacy and safety profiles. These analogs and derivatives undergo rigorous testing and clinical trials to ensure their effectiveness, tolerability, and potential for abuse.

It is important to note that methadone and its derivatives are potent opioids with the potential for addiction and misuse. Therefore, their use is strictly regulated and monitored by healthcare professionals to ensure safe and appropriate administration.

Chemical derivatives
The methade series includes the following compounds:


 * Acetylmethadol
 * Alphacetylmethadol
 * Levacetylmethadol
 * Betacetylmethadol)
 * Dimepheptanol (or methadol)
 * Alphamethadol
 * Betamethadol
 * Methadone
 * Levomethadone
 * Noracymethadol
 * Normethadone

Related compounds
Some related compounds include:


 * Alimadol
 * Dextromoramide
 * Dextropropoxyphene
 * Dimenoxadol
 * Dioxaphetyl butyrate
 * Dipipanone
 * Isomethadone
 * Normethadone
 * Norpipanone
 * Phenadoxone