Mighty Mac

Mighty Mac or Mighty Macs may refer to:


 * Mackinac Bridge, a suspension bridge in Michigan known as the Mighty Mac
 * Mighty Mac, nickname of the USS McKean (DD-784), a destroyer
 * Mighty Mac, nickname of the USS McClusky (FFG-41), a frigate
 * Mighty Mac, nickname of the USS Mackinac (AVP-13), a seaplane tender
 * The Mighty Mac, winning horse in the 1981 Powers Gold Cup and 1984 Cathcart Challenge Cup
 * Mighty Macs, nickname of the sports teams of Immaculata University, formerly Immaculata College
 * The Mighty Macs, a 2009 film about the women's basketball team of what was then Immaculata College
 * Mighty Mac, nickname of the sports teams of Bishop McNamara High School, Forestville, Maryland
 * Mighty Macs, nickname of the sports teams of Mother McAuley Liberal Arts High School, Chicago, Illinois