Mike Jacobs

Mike Jacobs may refer to:


 * Mike Jacobs (first baseman) (born 1980), American baseball player; first North American in professional sports to be tested positive for HGH
 * Mike Jacobs (shortstop) (1877–1949), played for the Chicago Cubs
 * Mike Jacobs (boxing) (1880–1953), American boxing promoter and member of the International Boxing Hall of Fame
 * Mike Jacobs (Georgia politician), representing District 80 in the Georgia House of Representatives
 * Mike Jacobs (Illinois politician) (born 1960), Illinois State Senator
 * Michael Jacobs (producer) (born 1955), American film and TV producer
 * Mike Jacobs, guitarist and songwriter for bands including The Pasties and Evil Jake
 * Mike Jacobs, former news anchor for WTMJ-TV in Milwaukee from 1977 to 2015\
 * Mike Jacobs (American football) (born c. 1978), American football coach