Miltiradiene synthase

Miltiradiene synthase (EC 4.2.3.131, SmMDS, SmiKSL) is an enzyme with systematic name (+)-copaly-diphosphate diphosphate-lyase (cyclizing, miltiradiene-forming). This enzyme catalyses the following chemical reaction


 * (+)-copalyl diphosphate $$\rightleftharpoons$$ miltiradiene + diphosphate

This enzyme is isolated from the plant Selaginella moellendorffii.