Mission Branch

Mission Branch is a stream in Bates County in the U.S. state of Missouri. It is a tributary of Sycamore Branch. The stream headwaters are at 38.14833°N, -94.21306°W and the stream flows to the southwest to its confluence with Sycamore Branch at 38.08778°N, -94.26222°W within the floodplain of the Marais des Cygnes River.

Mission Branch took its name from an Indian mission near its banks.