Mission High School

Mission High School may refer to:


 * Mission High School (San Francisco, California), a public high school in the San Francisco Unified School District (SFUSD) San Francisco, California
 * Mission High School (Mission, Texas), a secondary school located in Mission, Texas
 * Mission Continuation High School (Los Angeles)
 * San Gabriel Mission High School, an all-girls Catholic College Preparatory high school
 * Mission San Jose High School, Fremont, California
 * Mission High School, Rawalpindi