Moesin

Moesin is a protein that in humans is encoded by the MSN gene.

Moesin (for membrane-organizing extension spike protein) is a member of the ERM protein family which includes ezrin and radixin. ERM proteins appear to function as cross-linkers between plasma membranes and actin-based cytoskeletons.

Moesin is localized to filopodia and other membranous protrusions that are important for cell–cell recognition and signaling and for cell movement.

Moesin has FERM domain at N-terminal.

Interactions
Moesin has been shown to interact with:


 * CD43
 * ICAM3
 * Neutrophil cytosolic factor 1,
 * Neutrophil cytosolic factor 4
 * VCAM-1
 * EZR