Mthembu

Mthembu may refer to:
 * Gideon Mthembu (born 1963), Swazi sports official and retired runner
 * Jackson Mthembu (1957–2021), South African politician
 * Precious Mthembu (born 1984), South African netball player
 * Ricardo Mthembu (1970–2020), South African politician
 * Russel Mthembu (born 1947), South African singer
 * Siphelele Mthembu (born 1987), South African footballer
 * Thabani Mthembu (born 1994), South African footballer