Mtshali

Mtshali is a South African surname that may refer to the following notable people:
 * Eric Mtshali, South African politician
 * Gugu Mtshali, South African politician
 * Lindokuhle Mtshali, South African soccer player
 * Lionel Mtshali (1935–2015), South African politician
 * Oswald Mbuyiseni Mtshali (born 1940), South African poet
 * Themba Mtshali, South African politician
 * Thembi Mtshali-Jones (born 1949), South African actress