Musakhel

Musakhel can refer to:
 * the Musakhel tribe of Afghanistan and Pakistan
 * Musakhel District, Afghanistan, part of the province of Khost, Afghanistan
 * Musakhel, Khost, the administrative centre of the district of the same name in the province of Khost, Afghanistan
 * Musakhail District, Pakistan, part of the province of Balochistan, Pakistan
 * Musakhel Bazar, an administrative centre of the district of the same name in the province of Balochistan, Pakistan
 * Musakhel, Punjab, a village in Mianwali district in the province of Punjab, Pakistan