Muskie (disambiguation)

The muskie is a species of freshwater fish native to North America.

Muskie may also refer to:


 * Muskie Act, nickname for the U.S. Clean Air Act of 1963
 * Muskie Muskrat, a character in American Deputy Dawg cartoons
 * Big Muskie, an enormous coal-mining dragline excavator used in Ohio, U.S.
 * Edmund Muskie (1914–1996), American politician
 * Jane Muskie (1927–2004), First Lady of Maine
 * Muskingum Fighting Muskies, team name for Muskingum University in New Concord, Ohio
 * Muskie, a 1996 IBM RS64 microprocessor used in AS/400 machines
 * Muskie 101, branding for radio station WHSM-FM in Hayward, Wisconsin, U.S.
 * Muskies, team name for Muscatine High School in Muscatine, Iowa, U.S.