My Best Friend

My Best Friend may refer to:


 * My Best Friend (2001 film), Greek film
 * My Best Friend (2006 film) (Mon Meilleur Ami), French film
 * My Best Friend (2018 film) (Mi mejor amigo), Argentine film
 * "My Best Friend" (Skippy the Bush Kangaroo), episode of Skippy the Bush Kangaroo
 * "My Best Friend" (Tim McGraw song), 1999
 * "My Best Friend" (Jefferson Airplane song), 1966
 * "My Best Friend", song by Annie from Anniemal
 * "My Best Friend", song by Weezer from Make Believe
 * "My Best Friend", a song by Yui Horie, see Music of Kurogane Communication