N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase

The enzyme N-acetylglucosamine-1-phosphodiester α-N-acetylglucosaminidase (EC 3.1.4.45)  catalyzes the reaction


 * glycoprotein N-acetyl- D -glucosaminyl-phospho- D -mannose + H2O $$\rightleftharpoons$$ N-acetyl- D -glucosamine + glycoprotein phospho- D -mannose

This enzyme belongs to the family of hydrolases, specifically those acting on phosphoric diester bonds. The systematic name is glycoprotein-N-acetyl- D -glucosaminyl-phospho- D -mannose N-acetyl- D -glucosaminylphosphohydrolase. Other names in common use include α-N-acetylglucosaminyl phosphodiesterase, lysosomal α-N-acetylglucosaminidase, phosphodiester glycosidase, α-N-acetyl- D -glucosamine-1-phosphodiester, N-acetylglucosaminidase, 2-acetamido-2-deoxy-α- D -glucose 1-phosphodiester, and acetamidodeoxyglucohydrolase.