N-acetylneuraminylgalactosylglucosylceramide b-1,4-N-acetylgalactosaminyltransferase

N-acetylneuraminylgalactosylglucosylceramide beta-1,4-N-acetylgalactosaminyltransferase (, is an enzyme   that catalyses the following chemical reaction:


 * UDP-N-acetyl-D-galactosamine + N-acetylneuraminyl-(2->3)-alpha-D-galactosyl-(1->4)-beta-D-glucosyl-(1<->1)-ceramide $$\rightleftharpoons$$ UDP + N-acetyl-D-galactosaminyl-(1->4)-beta-N-acetylneuraminyl-(2->3)-alpha-D-galactosyl-(1->4)-beta-D-glucosyl-(1<->1)-ceramide

This enzyme requires Mn2+.

Nomenclature
This enzyme is also known as uridine diphosphoacetylgalactosamine-acetylneuraminyl(alpha2->3)galactosyl(beta1->4)glucosyl beta1->4-acetylgalactosaminyltransferase, UDP-N-acetyl-D-galactosamine:N-acetylneuraminyl-2,3-alpha-D-galactosyl-1,4-beta-D-glucosylceramide beta-1,4-N-acetylgalactosaminyltransferase) with systematic name UDP-N-acetyl-D-galactosamine:N-acetylneuraminyl-(2->3)-alpha-D-galactosyl-(1->4)-beta-D-glucosyl-(1<->1)-ceramide 4-beta-N-acetylgalactosaminyltransferase.