N-acetylphosphatidylethanolamine-hydrolysing phospholipase D

N-acetylphosphatidylethanolamine-hydrolysing phospholipase D (EC 3.1.4.54, NAPE-PLD, anandamide-generating phospholipase D, N-acyl phosphatidylethanolamine phospholipase D, NAPE-hydrolyzing phospholipase D') is an enzyme with systematic name 'N-acetylphosphatidylethanolamine phosphatidohydrolase''. It catalyses the following chemical reaction


 * N-acylphosphatidylethanolamine + H2O $$\rightleftharpoons$$ N-acylethanolamine + a 1,2-diacylglycerol 3-phosphate

This enzyme is involved in the biosynthesis of anandamide.